Estimated effectiveness of symptom and risk screening to prevent the spread of COVID-19.
Identifieur interne : 000662 ( 2020/Analysis ); précédent : 000661; suivant : 000663Estimated effectiveness of symptom and risk screening to prevent the spread of COVID-19.
Auteurs : Katelyn Gostic [États-Unis] ; Ana Cr Gomez [États-Unis] ; Riley O. Mummah [États-Unis] ; Adam J. Kucharski [Royaume-Uni] ; James O. Lloyd-Smith [États-Unis]Source :
- eLife [ 2050-084X ] ; 2020.
Descripteurs français
- KwdFr :
- Dépistage systématique (), Dépistage systématique (normes), Flambées de maladies, Humains, Infections asymptomatiques, Infections à coronavirus (diagnostic), Infections à coronavirus (transmission), Infections à coronavirus (épidémiologie), Lutte contre l'infection, Pneumopathie virale (diagnostic), Pneumopathie virale (transmission), Pneumopathie virale (épidémiologie), Voyage, Évaluation des risques.
- MESH :
- diagnostic : Infections à coronavirus, Pneumopathie virale.
- normes : Dépistage systématique.
- épidémiologie : Infections à coronavirus, Pneumopathie virale.
- Dépistage systématique, Flambées de maladies, Humains, Infections asymptomatiques, Lutte contre l'infection, Voyage, Évaluation des risques.
English descriptors
- KwdEn :
- Asymptomatic Infections, Betacoronavirus (isolation & purification), Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), Coronavirus Infections (transmission), Disease Outbreaks, Humans, Infection Control, Mass Screening (methods), Mass Screening (standards), Pneumonia, Viral (diagnosis), Pneumonia, Viral (epidemiology), Pneumonia, Viral (transmission), Risk Assessment, Travel.
- MESH :
- diagnosis : Coronavirus Infections, Pneumonia, Viral.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- isolation & purification : Betacoronavirus.
- methods : Mass Screening.
- standards : Mass Screening.
- transmission : Coronavirus Infections, Pneumonia, Viral.
- Asymptomatic Infections, Disease Outbreaks, Humans, Infection Control, Risk Assessment, Travel.
Abstract
Traveller screening is being used to limit further spread of COVID-19 following its recent emergence, and symptom screening has become a ubiquitous tool in the global response. Previously, we developed a mathematical model to understand factors governing the effectiveness of traveller screening to prevent spread of emerging pathogens (Gostic et al., 2015). Here, we estimate the impact of different screening programs given current knowledge of key COVID-19 life history and epidemiological parameters. Even under best-case assumptions, we estimate that screening will miss more than half of infected people. Breaking down the factors leading to screening successes and failures, we find that most cases missed by screening are fundamentally undetectable, because they have not yet developed symptoms and are unaware they were exposed. Our work underscores the need for measures to limit transmission by individuals who become ill after being missed by a screening program. These findings can support evidence-based policy to combat the spread of COVID-19, and prospective planning to mitigate future emerging pathogens.
DOI: 10.7554/eLife.55570
PubMed: 32091395
Affiliations:
- Royaume-Uni, États-Unis
- Angleterre, Californie, Grand Londres, Illinois
- Chicago, Londres, Los Angeles
- Université de Chicago
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000759
- to stream PubMed, to step Curation: 000759
- to stream PubMed, to step Checkpoint: 000525
- to stream Ncbi, to step Merge: 003217
- to stream Ncbi, to step Curation: 003217
- to stream Ncbi, to step Checkpoint: 003217
- to stream Main, to step Merge: 000662
- to stream Main, to step Curation: 000662
- to stream Main, to step Exploration: 000662
- to stream 2020, to step Extraction: 000662
Links to Exploration step
pubmed:32091395Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Estimated effectiveness of symptom and risk screening to prevent the spread of COVID-19.</title>
<author><name sortKey="Gostic, Katelyn" sort="Gostic, Katelyn" uniqKey="Gostic K" first="Katelyn" last="Gostic">Katelyn Gostic</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Ecology and Evolution, University of Chicago, Chicago, United States.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Ecology and Evolution, University of Chicago, Chicago</wicri:regionArea>
<placeName><settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
<orgName type="university">Université de Chicago</orgName>
</affiliation>
</author>
<author><name sortKey="Gomez, Ana Cr" sort="Gomez, Ana Cr" uniqKey="Gomez A" first="Ana Cr" last="Gomez">Ana Cr Gomez</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, United States.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles</wicri:regionArea>
<placeName><settlement type="city">Los Angeles</settlement>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mummah, Riley O" sort="Mummah, Riley O" uniqKey="Mummah R" first="Riley O" last="Mummah">Riley O. Mummah</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, United States.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles</wicri:regionArea>
<placeName><settlement type="city">Los Angeles</settlement>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kucharski, Adam J" sort="Kucharski, Adam J" uniqKey="Kucharski A" first="Adam J" last="Kucharski">Adam J. Kucharski</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Disease Epidemiology, London School of Tropical Hygiene and Medicine, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Infectious Disease Epidemiology, London School of Tropical Hygiene and Medicine, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lloyd Smith, James O" sort="Lloyd Smith, James O" uniqKey="Lloyd Smith J" first="James O" last="Lloyd-Smith">James O. Lloyd-Smith</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, United States.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles</wicri:regionArea>
<placeName><settlement type="city">Los Angeles</settlement>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2020">2020</date>
<idno type="RBID">pubmed:32091395</idno>
<idno type="pmid">32091395</idno>
<idno type="doi">10.7554/eLife.55570</idno>
<idno type="wicri:Area/PubMed/Corpus">000759</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000759</idno>
<idno type="wicri:Area/PubMed/Curation">000759</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000759</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000525</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000525</idno>
<idno type="wicri:Area/Ncbi/Merge">003217</idno>
<idno type="wicri:Area/Ncbi/Curation">003217</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">003217</idno>
<idno type="wicri:Area/Main/Merge">000662</idno>
<idno type="wicri:Area/Main/Curation">000662</idno>
<idno type="wicri:Area/Main/Exploration">000662</idno>
<idno type="wicri:Area/2020/Extraction">000662</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Estimated effectiveness of symptom and risk screening to prevent the spread of COVID-19.</title>
<author><name sortKey="Gostic, Katelyn" sort="Gostic, Katelyn" uniqKey="Gostic K" first="Katelyn" last="Gostic">Katelyn Gostic</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Ecology and Evolution, University of Chicago, Chicago, United States.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Ecology and Evolution, University of Chicago, Chicago</wicri:regionArea>
<placeName><settlement type="city">Chicago</settlement>
<region type="state">Illinois</region>
</placeName>
<orgName type="university">Université de Chicago</orgName>
</affiliation>
</author>
<author><name sortKey="Gomez, Ana Cr" sort="Gomez, Ana Cr" uniqKey="Gomez A" first="Ana Cr" last="Gomez">Ana Cr Gomez</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, United States.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles</wicri:regionArea>
<placeName><settlement type="city">Los Angeles</settlement>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mummah, Riley O" sort="Mummah, Riley O" uniqKey="Mummah R" first="Riley O" last="Mummah">Riley O. Mummah</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, United States.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles</wicri:regionArea>
<placeName><settlement type="city">Los Angeles</settlement>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kucharski, Adam J" sort="Kucharski, Adam J" uniqKey="Kucharski A" first="Adam J" last="Kucharski">Adam J. Kucharski</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Disease Epidemiology, London School of Tropical Hygiene and Medicine, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Infectious Disease Epidemiology, London School of Tropical Hygiene and Medicine, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lloyd Smith, James O" sort="Lloyd Smith, James O" uniqKey="Lloyd Smith J" first="James O" last="Lloyd-Smith">James O. Lloyd-Smith</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, United States.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles</wicri:regionArea>
<placeName><settlement type="city">Los Angeles</settlement>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">eLife</title>
<idno type="eISSN">2050-084X</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Asymptomatic Infections</term>
<term>Betacoronavirus (isolation & purification)</term>
<term>Coronavirus Infections (diagnosis)</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Coronavirus Infections (transmission)</term>
<term>Disease Outbreaks</term>
<term>Humans</term>
<term>Infection Control</term>
<term>Mass Screening (methods)</term>
<term>Mass Screening (standards)</term>
<term>Pneumonia, Viral (diagnosis)</term>
<term>Pneumonia, Viral (epidemiology)</term>
<term>Pneumonia, Viral (transmission)</term>
<term>Risk Assessment</term>
<term>Travel</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Dépistage systématique ()</term>
<term>Dépistage systématique (normes)</term>
<term>Flambées de maladies</term>
<term>Humains</term>
<term>Infections asymptomatiques</term>
<term>Infections à coronavirus (diagnostic)</term>
<term>Infections à coronavirus (transmission)</term>
<term>Infections à coronavirus (épidémiologie)</term>
<term>Lutte contre l'infection</term>
<term>Pneumopathie virale (diagnostic)</term>
<term>Pneumopathie virale (transmission)</term>
<term>Pneumopathie virale (épidémiologie)</term>
<term>Voyage</term>
<term>Évaluation des risques</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Mass Screening</term>
</keywords>
<keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Dépistage systématique</term>
</keywords>
<keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Mass Screening</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Asymptomatic Infections</term>
<term>Disease Outbreaks</term>
<term>Humans</term>
<term>Infection Control</term>
<term>Risk Assessment</term>
<term>Travel</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Dépistage systématique</term>
<term>Flambées de maladies</term>
<term>Humains</term>
<term>Infections asymptomatiques</term>
<term>Lutte contre l'infection</term>
<term>Voyage</term>
<term>Évaluation des risques</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Traveller screening is being used to limit further spread of COVID-19 following its recent emergence, and symptom screening has become a ubiquitous tool in the global response. Previously, we developed a mathematical model to understand factors governing the effectiveness of traveller screening to prevent spread of emerging pathogens (Gostic et al., 2015). Here, we estimate the impact of different screening programs given current knowledge of key COVID-19 life history and epidemiological parameters. Even under best-case assumptions, we estimate that screening will miss more than half of infected people. Breaking down the factors leading to screening successes and failures, we find that most cases missed by screening are fundamentally undetectable, because they have not yet developed symptoms and are unaware they were exposed. Our work underscores the need for measures to limit transmission by individuals who become ill after being missed by a screening program. These findings can support evidence-based policy to combat the spread of COVID-19, and prospective planning to mitigate future emerging pathogens.</div>
</front>
</TEI>
<affiliations><list><country><li>Royaume-Uni</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Californie</li>
<li>Grand Londres</li>
<li>Illinois</li>
</region>
<settlement><li>Chicago</li>
<li>Londres</li>
<li>Los Angeles</li>
</settlement>
<orgName><li>Université de Chicago</li>
</orgName>
</list>
<tree><country name="États-Unis"><region name="Illinois"><name sortKey="Gostic, Katelyn" sort="Gostic, Katelyn" uniqKey="Gostic K" first="Katelyn" last="Gostic">Katelyn Gostic</name>
</region>
<name sortKey="Gomez, Ana Cr" sort="Gomez, Ana Cr" uniqKey="Gomez A" first="Ana Cr" last="Gomez">Ana Cr Gomez</name>
<name sortKey="Lloyd Smith, James O" sort="Lloyd Smith, James O" uniqKey="Lloyd Smith J" first="James O" last="Lloyd-Smith">James O. Lloyd-Smith</name>
<name sortKey="Mummah, Riley O" sort="Mummah, Riley O" uniqKey="Mummah R" first="Riley O" last="Mummah">Riley O. Mummah</name>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Kucharski, Adam J" sort="Kucharski, Adam J" uniqKey="Kucharski A" first="Adam J" last="Kucharski">Adam J. Kucharski</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/2020/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000662 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/2020/Analysis/biblio.hfd -nk 000662 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= 2020 |étape= Analysis |type= RBID |clé= pubmed:32091395 |texte= Estimated effectiveness of symptom and risk screening to prevent the spread of COVID-19. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/2020/Analysis/RBID.i -Sk "pubmed:32091395" \ | HfdSelect -Kh $EXPLOR_AREA/Data/2020/Analysis/biblio.hfd \ | NlmPubMed2Wicri -a SrasV1
This area was generated with Dilib version V0.6.33. |